BDBM50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15

SMILES CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12

InChI Key InChIKey=ZPEIMTDSQAKGNT-UHFFFAOYSA-N

Data  238 KI  79 IC50  4 Kd  9 EC50

PDB links: 10 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50001888   

TargetD(1A) dopamine receptor(Mus musculus (Mouse))
Novo Industri

Curated by PDSP Ki Database
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataKi:  25nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
UniversitÉ

Curated by PDSP Ki Database
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataKi:  25nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
UniversitÉ

Curated by PDSP Ki Database
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataKi:  35nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
UniversitÉ

Curated by PDSP Ki Database
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataKi:  35nMAssay Description:Binding affinity against dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
UniversitÉ

Curated by PDSP Ki Database
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataKi:  35nMAssay Description:In vitro binding affinity against Dopamine receptor D1 in rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataKi:  44nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetD(1A) dopamine receptor(RAT)
UniversitÉ

Curated by PDSP Ki Database
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataKi:  50nMAssay Description:Inhibition of [3H]SCH-23,390 binding to Dopamine receptor D1 at 0.25 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataKi:  73nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(1A) dopamine receptor(RAT)
UniversitÉ

Curated by PDSP Ki Database
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataKi:  74nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataKi:  96nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(1A) dopamine receptor(BOVINE)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataKi:  113nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(1A) dopamine receptor(RAT)
UniversitÉ

Curated by PDSP Ki Database
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataKi:  140nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(BOVINE)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataKi:  900nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(BOVINE)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataKi:  900nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(1A) dopamine receptor(RAT)
UniversitÉ

Curated by PDSP Ki Database
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataIC50:  2.15nMAssay Description:Binding affinity against Dopamine receptor D1 by using [3H]-SCH-23,390 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed